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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IQGAP2 All Species: 31.82
Human Site: T917 Identified Species: 77.78
UniProt: Q13576 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13576 NP_006624.2 1575 180578 T917 K S T K F M D T V I F T L Y N
Chimpanzee Pan troglodytes XP_001146396 1575 180717 T917 K S T K F M D T V I F T L Y N
Rhesus Macaque Macaca mulatta XP_001114017 1632 184597 A989 K T T K F M E A V I F S L Y N
Dog Lupus familis XP_536318 1641 188145 T983 K S T K F M D T V I F T L Y N
Cat Felis silvestris
Mouse Mus musculus Q3UQ44 1575 180509 T917 K S T K F M D T V I F T L Y N
Rat Rattus norvegicus NP_001101959 1657 188814 S1004 K S T K F M D S V I F T L Y N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_413959 2023 228609 S1370 K S T K F M D S V I F T L Y N
Frog Xenopus laevis NP_001082588 1660 189688 T1000 K S T K F M D T V I F T L Y N
Zebra Danio Brachydanio rerio NP_001121812 1680 191619 T1013 K S T K F M D T V I F T L Y N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203784 771 87814 Q157 G V D R A N K Q T I A A N K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 50.3 86.7 N.A. 88.9 58.2 N.A. N.A. 48.7 66.6 61.4 N.A. N.A. N.A. N.A. 25.2
Protein Similarity: 100 99.8 69 91.5 N.A. 95.3 74.7 N.A. N.A. 61.5 78 75.8 N.A. N.A. N.A. N.A. 38.3
P-Site Identity: 100 100 73.3 100 N.A. 100 93.3 N.A. N.A. 93.3 100 100 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 10 0 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 80 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 90 0 0 0 0 0 90 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % I
% Lys: 90 0 0 90 0 0 10 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 90 0 10 % L
% Met: 0 0 0 0 0 90 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 90 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 80 0 0 0 0 0 20 0 0 0 10 0 0 0 % S
% Thr: 0 10 90 0 0 0 0 60 10 0 0 80 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 90 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 90 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _